Selenium and gastrointestinal cancers risk
نویسندگان
چکیده
Material and methods The research material was a total of 110 samples of blood serum from people with cancer, diagnosed and confirmed in one of the organs: colon (67 cases), pancreas (30 cases) or stomach (13 cases) and 110 samples of blood serum derived from healthy individuals representing paired control group. The criteria adopted for pairing included: gender, year of birth (+/3 years), history of the occurrence of cancers in the family among first degree relatives and smoking status expressed in pack-years. Selenium concentration in blood serum was determined using inductively coupled plasma mass spectrometry (ICP-MS) – Perkin Elmer. Validation: Seronorm, Nycomed Pharma AS, Oslo, Norway. The measurement accuracy was +/5% μg Se/l.
منابع مشابه
Ecologic study of serum selenium and upper gastrointestinal cancers in Iran.
AIM Both observational and experimental studies have shown that higher selenium status reduces the risk of upper gastrointestinal cancers in selenium deficient populations. Recent cancer registry data have shown very different rates of esophageal cancer (EC) and gastric cancer (GC) in four Provinces of Iran, namely Ardabil, Mazandaran, Golestan, and Kerman. The aim of this study was to have a p...
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